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Table 3 Gene knockout analysis

From: Further developments towards a genome-scale metabolic model of yeast

 

iMM904

iIN800

Yeast 4.0

number of genes

904

707

924

true positive (%)

75.0

69.7

74.8

true negative (%)

5.1

6.9

5.3

false positive (%)

9.3

10.6

11.1

false negative (%)

10.6

12.7

8.8

  1. Results of in silico viability prediction of deletion strains of S. cerevisiae. "Positive" and "negative" refer to the ability and inability to grow, respectively. Following earlier studies, the knockout simulation was conducted in a glucose-limited minimal medium, and compared to experimental knockout data [30, 31].
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BMC Systems Biology

ISSN: 1752-0509

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