Figure 6

Simulation results for the iron content profiles over time. Simulation results for the iron content profiles over time for cLIP and ferritin species: (A) when a pulse of free iron is introduced into the system at t = 1.0 simulation time units. The pulse of iron given to the system was equal to the steady state amount of iron in the cLIP; (B) when all iron in the cLIP is washed out of the system at t = 1.0 simulation time units; (C) when a pulse of free iron is introduced into the system at t = 1.0 simulation time units. In this case the pulse of iron given to the system was equal to 20 times the steady state amount of iron in the cLIP, doubling the total iron in the system.