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Figure 2 | BMC Systems Biology

Figure 2

From: A genetic network model of cellular responses to lithium treatment and cocaine abuse in bipolar disorder

Figure 2

Network Hypothesis. The network developed models the complex gene-by-environment interactions involved in both lithium etiology and comorbid cocaine abuse associated with BD. Consistent with our initial hypothesis, the network is significantly over-represented for genes associated with signal transduction. In addition, the network models related pharmacogenomic, psychiatric, and chemical dependence phenotypes.

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