Figure 6
From: Confidence from uncertainty - A multi-target drug screening method from robust control theory
Robust performance analysis and results of one robust therapy in presence of parametric uncertainty. (A) Results of the SSV analysis applied for robust performance, in presence of parametric uncertainty. Green and red dots illustrate therapies that pass and do not pass the robust performance selection criterion, respectively. (B) Comparison between the performance envelopes described in Figure 3A and the results obtained from therapy no. 30. Blue curves are the simulation results by therapy 30 linearized model with 100 different parameter sets, sampled within ± 45% of the nominal values. Gray curves are the upper and lower bounds of the stochastic envelope generated by the Stochastic Simulation Algorithm of therapy 30 nonlinear model (mean ± standard deviation of 100 trajectories).