Regulation patterns in signaling networks of cancer

BMC Systems Biology

Table 1 Network sizes

	Links in the whole network	Nodes in the whole network	Number of receptors	Number of transcription factors	Percentage of used nodes		Percentage of used links		Average distances of two neighbored nodes (d_xy)
					normal	tumor	normal	tumor	normal	tumor
AML 1	29211	7244	653	578	39.1	48.8	55.5	69.7	0.32	0.59
AML 2	23181	5574	559	505	36.4	52.7	48.5	72.9	0.07	0.72
Breast 1	29211	7244	653	578	45.7	46.2	65.7	66.3	0.57	0.59
Breast 2	33722	8651	706	617	39.1	40.1	57.6	59.4	0.47	0.53
Cervical 1	33722	8651	706	617	33.7	43.5	47.4	64.9	0.20	0.52
Cervical 2	29211	7244	653	578	43.2	46.8	61.0	66.6	0.38	0.54
ESCC	29211	7244	653	578	45.6	49.9	65.4	71.5	0.51	0.73
Glioma	33722	8651	706	617	39.1	42.0	56.6	62.6	0.36	0.58
Head and neck	23181	5574	559	505	45.8	45.7	62.0	62.0	0.38	0.41
Lung 1	23181	5574	559	505	48.7	48.4	67.2	67.8	0.47	0.47
Lung 2	29211	7244	653	578	44.4	45.6	62.6	65.3	0.43	0.48
Oral tongue 1	23181	5574	559	505	46.5	50.5	63.4	70.0	0.40	0.59
Oral tongue 2	33722	8651	706	617	40.3	42.9	59.6	63.5	0.39	0.54
Pancreas 1	33722	8651	706	617	33.6	42.7	46.4	63.2	0.26	0.53
Pancreas 2	33722	8651	706	617	33.2	43.4	46.3	64.3	0.25	0.57
Prostate 1	23181	5574	559	505	39.5	41.6	50.0	53.7	0.28	0.34
Prostate 2	33722	8651	706	617	41.0	43.6	60.6	64.9	0.41	0.57
Renal 1	29211	7244	653	578	44.1	44.4	63.9	64.3	0.41	0.42
Renal 2	33722	8651	706	617	29.5	41.2	40.2	61.0	0.07	0.54
Vulva	33722	8651	706	617	38.8	39.2	57.8	58.2	0.34	0.36

ISSN: 1752-0509