Regulation patterns in signaling networks of cancer

BMC Systems Biology

Table 2 Statistics of general network features

	Number of links		Exponent α		Link frequency		Node frequency		Path length		Increase of path length
	normal	tumor	normal	tumor	normal	tumor	normal	tumor	normal	tumor	normal	tumor
AML 1	16224	20367	1.24	1.28	200	101	720	461	5.40	4.32	1.67	1.57
AML 2	11245	16896	0.98	1.30	719	82	1256	384	9.02	3.99	2.04	1.55
Breast 1	19188	19357	1.27	1.28	113	108	502	487	4.40	4.32	1.59	1.62
Breast 2	19408	20031	1.22	1.23	147	134	605	573	4.70	4.57	1.65	1.63
Cervical 1	15983	21877	1.12	1.26	330	121	962	537	6.41	4.64	1.65	1.58
Cervical 2	17833	19463	1.23	1.27	152	112	613	500	5.09	4.49	1.54	1.58
ESCC	19107	20887	1.25	1.29	122	89	534	424	4.67	4.06	1.56	1.53
Glioma	19102	21114	1.18	1.27	172	120	673	543	5.23	4.53	1.55	1.56
Head and neck	14365	14364	1.23	1.26	141	136	554	539	5.01	4.87	1.59	1.58
Lung 1	15568	15722	1.24	1.28	116	116	484	489	4.65	4.67	1.62	1.58
Lung 2	18295	19080	1.24	1.25	135	121	563	525	4.80	4.60	1.59	1.54
Oral tongue 1	14698	16223	1.23	1.27	136	94	533	432	4.89	4.31	1.61	1.55
Oral tongue 2	20097	21406	1.22	1.25	163	123	649	534	5.19	4.55	1.62	1.62
Pancreas 1	15661	21307	1.18	1.25	230	123	798	536	5.32	4.55	1.65	1.60
Pancreas 2	15604	21671	1.17	1.25	256	113	841	509	5.54	4.39	1.63	1.59
Prostate 1	11590	12450	1.15	1.19	184	154	672	600	5.25	4.93	1.56	1.58
Prostate 2	20446	21899	1.23	1.27	156	114	615	510	5.01	4.42	1.72	1.62
Renal 1	18660	18791	1.25	1.26	148	144	582	581	4.93	4.95	1.70	1.66
Renal 2	13557	20567	1.02	1.26	702	126	1371	552	8.02	4.52	1.55	1.59
Vulva	19491	19612	1.22	1.22	192	185	700	688	5.39	5.36	1.72	1.73
Tendency for tumor	Up		Up		Down		Down		Down		Down
Significance (P-value)	3.81E-06		1.91E-06		3.81E-06		5.72E-06		5.37E-06		0.021

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