Table 4 Experimentally verified targets.
From: Integrated analysis of mutations, miRNA and mRNA expression in glioblastoma
miRNA | P-value for differential expression of miRNA | Up or down regulated miRNA | Gene | P-value for differential expression of gene | Up or down regulated gene | Regression coefficient | P-value for testing association of miRNA with target mRNA | Coefficient of determination | Function of gene | References |
|---|---|---|---|---|---|---|---|---|---|---|
mir-124a | 8.62E-08 | Down | CTDSP1 | 8.4E-07 | Up | -17.7 | 2.22E-16 | 0.244 | Â | [42] |
mir-155 | 1.31E-07 | Up | LDOC1 | 1.67E-07 | Down | -197 | 4.00E-15 | 0.223 | tumor suppressor | [47] |
mir-155 | 1.31E-07 | Up | SCAMP1 | 3.27E-06 | Down | -30.9 | 6.06E-10 | 0.145 | Â | [43] |
mir-16 | 0.0000178 | Up | RTN4 | 9.44E-08 | Down | -766 | 2.66E-08 | 0.119 | tumor suppressor | [43] |
mir-16 | 0.0000178 | Up | SLC25A22 | 3.36E-08 | Down | -37.8 | 1.97E-11 | 0.168 | Â | [43] |
mir-16 | 0.0000178 | Up | VTI1B | 7.15E-08 | Down | -122 | 1.03E-05 | 0.0765 | Â | [43] |
mir-21 | 9.98E-08 | Up | BASP1 | 2.98E-08 | Down | -743 | 0.00E+00 | 0.349 | Â | [44] |
mir-21 | 9.98E-08 | Up | RTN4 | 9.44E-08 | Down | -246 | 1.16E-05 | 0.0756 | Â | [44] |
mir-210 | 1.48E-06 | Up | EFNA3 | 4.67E-07 | Down | -10.4 | 4.61E-05 | 0.0657 | Â | [48] |
mir-29b | 2.07E-07 | Down | COL4A2 | 1.83E-07 | Up | -164 | 8.92E-05 | 0.0609 | Â | [50] |
mir-29c | 3.66E-07 | Down | COL4A2 | 1.83E-07 | Up | -260 | 1.99E-07 | 0.105 | Â | [49] |
mir-29c | 3.66E-07 | Down | COL4A1 | 4.91E-08 | Up | -389 | 1.35E-08 | 0.124 | Â | [49] |
mir-29c | 3.66E-07 | Down | TDG | 5.21E-07 | Up | -95.5 | 3.22E-14 | 0.21 | Â | [49] |
mir-33 | 9.6317E-06 | Down | ABCA1 | 1.0396E-06 | Up | -114.5 | 5.941E-12 | 0.176 | Â | [51] |