Figure 8

Network of protein interactions and gene/protein stimulations and inhibitions involved in pluripotency, condensed using ExprEssence and microarray data tracking the transition process from embryonic stem to epiblast-like cell state. Expression values for Trim28, Esrrb, Klf4, Klf2, Klf5 are inlineed to the left (ES state) and to the right (epiblast state) of the gene (node). Esrrb and Trim28 are both found in the upper right corner.