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Figure 3 | BMC Systems Biology

Figure 3

From: Systems biology approach reveals that overflow metabolism of acetate in Escherichia coli is triggered by carbon catabolite repression of acetyl-CoA synthetase

Figure 3

Dilution rate dependent intracellular metabolite patterns in one E. coli A-stat experiment. D, dilution rate (h-1). (A) Pentose phosphate pathway metabolites. R5P, ribose-5-phosphate concentration (black diamond); E4P, erythrose-4-phosphate concentration (open circle). (B) TCA cycle metabolites and co-factor free CoA. α-KG, α-ketoglutarate concentration (black diamond); Cit/Ici, citrate/isocitrate pool concentration (open circle); HS-CoA, co-factor free CoA level (grey triangle). (C) Glycolysis (upper part) metabolites. FBP, fructose-1,6-bisphosphate concentration (black diamond); GAP, glyceraldehyde-3-phosphate concentration (open circle).

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BMC Systems Biology

ISSN: 1752-0509

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