Figure 5From: Systems biology approach reveals that overflow metabolism of acetate in Escherichia coli is triggered by carbon catabolite repression of acetyl-CoA synthetaseDilution rate dependent acetic acid consumption capability in E. coli D-stat cultures. KOAc-, acetic acid consumption per biomass (red triangle); OAc-, acetate concentration in chemostat before the start of acetic acid supplemented medium addition (violet circle); cAMP, cyclic AMP concentration (blue square); Acs, acetyl-CoA synthetase protein dilution rate dependent expression levels from A-stat (green diamond). Error bars represent the standard deviation from two independent D-stat experiments.Back to article page