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Figure 2 | BMC Systems Biology

Figure 2

From: Defining the antigen receptor-dependent regulatory network that induces arrest of cycling immature B-lymphocytes

Figure 2

BCR-dependent modulation of TF activities. Panel A shows the representative arrays of transcription factor activation in CH1 cells in response to anti-IgM. Cells were stimulated with anti-IgM and the activation profiles of transcription factors probed by TF array either in unstimulated cells, or in cells stimulated for either 20 or 40 min with anti-IgM. Where, the unstimulated cells were treated as control. Plot in the panel B shows the quantified changes observed in the TF activity upon stimulation of CH1 cells with anti-IgM. Only the subset of TFs that showed >2 fold activation or repression in activity in either of the time points were plotted in log10 scale after. The nomenclature used to denote the TFs are the aliases provided by the array manufacturer, their corresponding Entrez Gene IDs are listed in Additional File 2.

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