The significance profile over time and the significance level by paired-SAM of metabolites in the tricarboxylic acid (TCA) cycle and amino acid biosynthesis pathways due to (a) NaCl stress on the control state (blue), (b) the elevated CO
conditions on the NaCl state (orange), and (c) the combined (NaCl + CO
) stress on the control state (purple). If a metabolite was identified as positively, negatively or nonsignificant at the n-th time point for a particular stress, then the n-th box with the corresponding to the stress borderline color next to the name of this metabolite is colored red, green or remains blank, respectively. The nine-th separate box in each line depicts the significance level of a metabolite for the particular stress as this was identified by paired-SAM. If metabolite was positively, negatively or nonsignificant by paired-SAM, a red upward arrow, a green downward arrow or a black vertical line is shown, respectively, in the nine-th box.