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Figure 3 | BMC Systems Biology

Figure 3

From: Understanding protein evolutionary rate by integrating gene co-expression with protein interactions

Figure 3

Co-expressed proteins evolve more slowly than non-co-expressed proteins. Protein evolutionary rate dN (y-axis) of non-co-expressed proteins (gray bars) and co-expressed proteins (dark gray bars) is shown as a function of PPID (x-axis). For the purpose of a detailed comparison, non-co-expressed and co-expressed proteins are further grouped into three bins (see Methods for details) according to their PPID values. (A) "Y2H-union" (B) "Combined-AP/MS" (C) "LC-multiple" (D) "Updated-HC" (E) "DIP-CORE" (F) "DIP-FULL".

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