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Table 4 Principal component regression analysis on six predictor variables and protein evolutionary rate for 752 yeast proteins in the "Y2H-union" dataset.

From: Understanding protein evolutionary rate by integrating gene co-expression with protein interactions

  Principal Components
  1 2 3 4 5 6 All
Percent variance explained in dN 34.13*** 0.55 0.46 0.38 0.23 0.00 35.74***
Percent contributions        
mRNA abundance 36.2 1.2 49.1 13.3 0.0 0.2  
protein abundance 37.3 1.7 50.7 10.2 0.0 0.0  
gene dispensability 10.4 2.0 0.0 37.2 49.9 0.4  
gene pleiotropy 11.3 0.0 0.1 38.9 49.2 0.4  
ePPID 3.9 45.4 0.0 0.3 0.4 49.9  
betweenness 0.8 49.6 0.1 0.1 0.4 49.0  
  1. Note: #P < 0.01; *P < 10-3; **P < 10-6; ***P < 10-9. Bold indicates that the predictor variable contributes at least 20% to the corresponding principal component.