Table 5 Principal component regression analysis on six predictor variables and protein evolutionary rate for 723 yeast proteins in the "Combined-AP/MS" dataset.
From: Understanding protein evolutionary rate by integrating gene co-expression with protein interactions
| Â | Principal Components | ||||||
|---|---|---|---|---|---|---|---|
| Â | 1 | 2 | 3 | 4 | 5 | 6 | All |
Percent variance explained in dN | 27.26*** | 7.77*** | 1.11* | 0.92# | 0.83# | 0.01 | 37.90*** |
Percent contributions | Â | Â | Â | Â | Â | Â | Â |
mRNA abundance | 24.3 | 9.0 | 14.6 | 47.3 | 0.3 | 4.4 | Â |
protein abundance | 22.8 | 15.9 | 13.4 | 41.3 | 0.1 | 6.5 | Â |
gene dispensability | 8.7 | 2.5 | 20.8 | 1.0 | 63.2 | 3.8 | Â |
gene pleiotropy | 0.0 | 37.2 | 40.1 | 0.0 | 20.6 | 2.1 | Â |
ePPID | 24.5 | 16.6 | 4.3 | 7.5 | 0.0 | 47.0 | Â |
betweenness | 19.7 | 18.9 | 6.8 | 2.8 | 15.8 | 36.1 | Â |