Table 6 Principal component regression analysis on six predictor variables and protein evolutionary rate for 639 yeast proteins in the "LC-multiple" dataset.
From: Understanding protein evolutionary rate by integrating gene co-expression with protein interactions
| Â | Principal Components | ||||||
|---|---|---|---|---|---|---|---|
| Â | 1 | 2 | 3 | 4 | 5 | 6 | All |
Percent variance explained in dN | 27.43*** | 6.90*** | 1.40* | 0.94# | 0.32 | 0.26 | 37.24*** |
Percent contributions | Â | Â | Â | Â | Â | Â | Â |
mRNA abundance | 21.4 | 22.0 | 50.1 | 6.0 | 0.0 | 0.5 | Â |
protein abundance | 20.7 | 21.7 | 44.3 | 6.3 | 1.6 | 5.3 | Â |
gene dispensability | 13.0 | 0.0 | 0.4 | 65.6 | 19.9 | 1.1 | Â |
gene pleiotropy | 2.8 | 25.6 | 0.8 | 22.0 | 48.6 | 0.2 | Â |
ePPID | 25.9 | 10.4 | 3.6 | 0.1 | 6.8 | 53.2 | Â |
betweenness | 16.3 | 20.3 | 0.7 | 0.0 | 23.0 | 39.7 | Â |