Integrated functional networks of process, tissue, and developmental stage specific interactions in Arabidopsis thaliana

BMC Systems Biology

Table 2 Development stages and tissues/biological processes of interest

Development Stage	Tissue/Biological Process	AUC	Level
C globular stage	meristem	0.822	Strong interaction with development
	leaf	0.818
	seed	0.754
D bilateral stage embryo dev stages flower dev stages	meristem	0.816	Strong interaction with development
		0.8
		0.79
0 germination flora organ dev stages flower dev stages	carpel	0.66	Weak interaction with development
		0.73
		0.71

These nine tissue/process contexts had sufficient overlapping curated information to evaluate our accuracy in predicting functional relationships occurring during a specific developmental stage within one tissue. For example, the meristem activates gene programs to differentiate into shoot and root tissues during the D bilateral stage [20], and we accurately recover these predicted interactions.