Simulations predicting experimental results. Time courses of A) [PKMζ] and B) EPSC amplitude after a weak stimulus, Stim(t) = 5 (0 ≤ t < 30), in the presence (solid line) or absence (dashed line) of a F-actin stabilizer. C) Steady-state [PKMζ] versus an actin polymerization rate, j
. The other actin polymerization rate, j
was treated as a dependent parameter (j
). D, E) [PKMζ mRNA] and bistability. D) Steady-state [PKMζ] versus the bifurcation parameter, [PKMζ mRNA]. E) The threshold [PKMζ mRNA] to perpetually activate the system.