TY - JOUR AU - Tolle, Dominic P. AU - Le Novère, Nicolas PY - 2010 DA - 2010/03/16 TI - Meredys, a multi-compartment reaction-diffusion simulator using multistate realistic molecular complexes JO - BMC Systems Biology SP - 24 VL - 4 IS - 1 AB - Most cellular signal transduction mechanisms depend on a few molecular partners whose roles depend on their position and movement in relation to the input signal. This movement can follow various rules and take place in different compartments. Additionally, the molecules can form transient complexes. Complexation and signal transduction depend on the specific states partners and complexes adopt. Several spatial simulator have been developed to date, but none are able to model reaction-diffusion of realistic multi-state transient complexes. SN - 1752-0509 UR - https://doi.org/10.1186/1752-0509-4-24 DO - 10.1186/1752-0509-4-24 ID - Tolle2010 ER -