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Table 3 DAVID Functional Annotation Clustering output for genes significantly differently expressed compared to controls following exposure to an approximate EC50 for each tested chemicals.

From: Linking toxicant physiological mode of action with induced gene expression changes in Caenorhabditis elegans

  Cd FA AZ
Cd_FA_AZ    
   membrane/transmembrane 8.61 7.85 1.39
   cation binding 5.08 2.35 4.22
   glycoprotein signalling 4.06 3.25 2.93
   transcriptional activity 2.88 0.93 1.75
   protease activity 2.64 1.04 1.6
   protein kinase activity 1.58 1.04 2
   signal tranduction activity 1.15 1.51 1
   ribosomal protein 0.87 3.75 4.12
Cd_FA    
   isomerase activity 1.55 1.35  
   EGF-like domain 0.94 0.95  
Cd_AZ    
   mitochondria 1.59   1.57
   homeobox 1.48   1.23
   collagen 0.67   0.63
   stress and heat shock chaperoning 2.28   1.49
FA_AZ    
   wd repeat   2.35 3.72
   nucleosome core and chromatin   1.36 2.13
   haem/monooxygenase   2.3 1.47
   ion transport   0.57 0.58
Cd    
   transcription factor activity 2.28   
   tansmembrane transport 2.21   
   thiol protease 0.75   
FA    
   oxidoreductase   3.96  
   mRNA splicing   2.83  
   amino acid biosynthesis   1.21  
   flavoprotein   0.95  
   protein biosynthesis initiation   0.63  
   protein biosynthesis tRNA synthesis   0.6  
AZ    
   larval development    5.1
   magnesium ion binding    1.5
   glycolosis    1.45
   threonine protease    0.97
   calcium    0.83
   acyltransferase    0.82
   ubiquitination    0.76