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Table 3 Receptors identified in our study and not yet studied in connection to psoriasis

From: Integrated network analysis of transcriptomic and proteomic data in psoriasis

Gene Protein Entrez Gene ID Connection to psoriasis
EPHA2 Ephrin-A receptor 2 1969 No
EPHB2 Ephrin-B receptor 2 2048 No
FCER1G Fc epsilon RI gamma 2207 No
INSR Insulin receptor 3643 No
LTBR LTBR(TNFRSF3) 4055 No
PLAUR PLAUR (uPAR) 5329 No
TNFRSF10A DR4(TNFRSF10A) 8797 No
TNFRSF10B DR4(TNFRSF10A) 8795 No
CD44 CD44 960 Possible[55]
CSF2RB CSF2RB 1439 Possible[56]
CXCR4 CXCR4 7852 Possible[57]
FZD4 FZD4 8322 Possible[58]
GABBR1 GBR1 2550 Possible[59]
IL10RA IL10RA 3587 Possible[60]
IL13RA1 IL13RA1 3597 Possible[61]
IL2RB IL-2R beta chain 3560 Possible[62]
IL2RG IL-2R gamma chain 3561 Possible[62]
IL4R IL4RA 3566 Possible[63]
LILRB2 ILT4 10288 Possible[64]
LRP2 LRP2 (Megalin) 4036 Possible[65]
LRP8 APOER2 7804 Possible[65]
ROR2 ROR2 4920 Possible[58]
AGER RAGE 177 Yes[66]
CCR1 CCR1 1230 Yes[67]
CCR2 CCR2 1231 Yes[68]
CCR3 CCR3 1232 Yes[69]
CCR5 CCR5 1234 Yes[70]
CD2 CD2 914 Yes[71]
CD27 CD27(TNFRSF7) 939 Yes[72]
CD36 CD36 948 Yes[73]
CD3D CD3 delta 915 Yes[74]
EGFR EGFR 1956 Yes[75]
IL17RA IL-17 receptor 23765 Yes[76]
IL1R1 IL-1RI 3554 Yes[77]
IL8RA IL8RA 3577 Yes[78]
IL8RB IL8RB 3579 Yes[78]
ITGAL ITGAL 3683 Yes[79]
ITGB2 ITGB2 3689 Yes[80]
LRP1 A2 M receptor 4035 Yes[81]
PTPRC CD45 5788 Yes[82]
SDC3 Syndecan-3 9672 Yes[83]
SELE E-selectin 6401 Yes[84]
SELPLG PSGL-1 6404 Yes[85]
TLR4 TLR4 7099 Yes[86]
  1. 'Possible' term was used if protein name co-occurred with psoriasis in articles, but no clear evidence of its implication was shown. In some cases, ligands are associated with psoriasis (i.e, IL-10).