Table 3 Receptors identified in our study and not yet studied in connection to psoriasis
From: Integrated network analysis of transcriptomic and proteomic data in psoriasis
Gene | Protein | Entrez Gene ID | Connection to psoriasis |
|---|---|---|---|
EPHA2 | Ephrin-A receptor 2 | 1969 | No |
EPHB2 | Ephrin-B receptor 2 | 2048 | No |
FCER1G | Fc epsilon RI gamma | 2207 | No |
INSR | Insulin receptor | 3643 | No |
LTBR | LTBR(TNFRSF3) | 4055 | No |
PLAUR | PLAUR (uPAR) | 5329 | No |
TNFRSF10A | DR4(TNFRSF10A) | 8797 | No |
TNFRSF10B | DR4(TNFRSF10A) | 8795 | No |
CD44 | CD44 | 960 | Possible[55] |
CSF2RB | CSF2RB | 1439 | Possible[56] |
CXCR4 | CXCR4 | 7852 | Possible[57] |
FZD4 | FZD4 | 8322 | Possible[58] |
GABBR1 | GBR1 | 2550 | Possible[59] |
IL10RA | IL10RA | 3587 | Possible[60] |
IL13RA1 | IL13RA1 | 3597 | Possible[61] |
IL2RB | IL-2R beta chain | 3560 | Possible[62] |
IL2RG | IL-2R gamma chain | 3561 | Possible[62] |
IL4R | IL4RA | 3566 | Possible[63] |
LILRB2 | ILT4 | 10288 | Possible[64] |
LRP2 | LRP2 (Megalin) | 4036 | Possible[65] |
LRP8 | APOER2 | 7804 | Possible[65] |
ROR2 | ROR2 | 4920 | Possible[58] |
AGER | RAGE | 177 | Yes[66] |
CCR1 | CCR1 | 1230 | Yes[67] |
CCR2 | CCR2 | 1231 | Yes[68] |
CCR3 | CCR3 | 1232 | Yes[69] |
CCR5 | CCR5 | 1234 | Yes[70] |
CD2 | CD2 | 914 | Yes[71] |
CD27 | CD27(TNFRSF7) | 939 | Yes[72] |
CD36 | CD36 | 948 | Yes[73] |
CD3D | CD3 delta | 915 | Yes[74] |
EGFR | EGFR | 1956 | Yes[75] |
IL17RA | IL-17 receptor | 23765 | Yes[76] |
IL1R1 | IL-1RI | 3554 | Yes[77] |
IL8RA | IL8RA | 3577 | Yes[78] |
IL8RB | IL8RB | 3579 | Yes[78] |
ITGAL | ITGAL | 3683 | Yes[79] |
ITGB2 | ITGB2 | 3689 | Yes[80] |
LRP1 | A2 M receptor | 4035 | Yes[81] |
PTPRC | CD45 | 5788 | Yes[82] |
SDC3 | Syndecan-3 | 9672 | Yes[83] |
SELE | E-selectin | 6401 | Yes[84] |
SELPLG | PSGL-1 | 6404 | Yes[85] |
TLR4 | TLR4 | 7099 | Yes[86] |