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Table 2 GO Terms assignment for intra-nuclear bodies.

From: The proteins of intra-nuclear bodies: a data-driven analysis of sequence, interaction and expression

Intra-nuclear body

GO Term

Description

E-Value

Nucleolus

GO:0042254

Ribosome biogenesis and assembly

1.80E-19

 

GO:0022613

Ribonucleoprotein complex biogenesis and assembly

3.30E-15

 

GO:0016072

rRNA metabolic process

3.30E-14

 

GO:0006364

rRNA processing

3.30E-14

 

GO:0009059

Macromolecule biosynthetic process

2.90E-08

 

GO:0043228

Non-membrane-bound organelle

3.30E-08

 

GO:0043232

Intracellular non-membrane-bound organelle

3.30E-08

 

GO:0006412

Translation

5.70E-08

 

GO:0009058

Biosynthetic process

1.20E-06

PML nuclear body

GO:0006950

Response to stress

6.10E-09

 

GO:0006974

Response to DNA damage stimulus

1.70E-08

 

GO:0009719

Response to endogenous stimulus

2.30E-08

 

GO:0050896

Response to stimulus

4.00E-07

 

GO:0006281

DNA repair

4.40E-05

 

GO:0042770

DNA damage response, signal transduction

5.90E-05

 

GO:0007049

Cell cycle

1.40E-03

 

GO:0006464

Protein modification process

1.60E-03

 

GO:0022402

Cell cycle process

2.70E-03

Nuclear Speckle

GO:0016071

mRNA metabolic process

1.20E-61

 

GO:0006397

mRNA processing

4.80E-61

 

GO:0008380

RNA splicing

1.20E-58

 

GO:0005681

Spliceosome

1.90E-38

 

GO:0006396

RNA processing

5.80E-34

 

GO:0030529

Ribonucleoprotein complex

1.90E-26

 

GO:0003723

RNA binding

2.00E-25

 

GO:0016070

RNA metabolic process

1.70E-06

 

GO:0000377

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile

4.10E-06

 

GO:0000398

Nuclear mRNA splicing, via spliceosome

4.10E-06

  1. For each compartment, GO terms assigned to member proteins that are also deemed significantly enriched (relative the terms assigned to the pool of nuclear proteins) are shown using the term ID and the description. The E-value is the Bonferroni corrected p-value of the term as determined by the Fisher's exact test (see Methods). The E-value is below 0.01 for all terms shown. GO terms for the nuclear compartments and their parts are excluded.