Figure 3

Sensitivity analysis of the circuit for the most outstanding parameters. The rest of the parameter values are shown in Table 1. We plot the steady state(s) (x _ss ) at very high levels of IPTG, i = 10³ (solid lines), and with no IPTG (dashed lines). Bifurcation of solid lines indicates the bistability limit condition. Bifurcation of dashed lines represents the oscillatory limit point, where we plot the maximal and minimal values of the oscillatory dynamics. In c, d AHL is externally introduced at very high levels.