Figure 5From: A formal model for analyzing drug combination effects and its application in TNF-α-induced NFκB pathwayNegative feedback structure. This system with negative feedback loop (from [1]) is constructed based on the serial system in Figure 1 by adding a feedback loop (orange color) which is from the output C-P to the activation of B to the serial structure. The output of this system is still the concentration of activation C.Back to article page