Correlation of the features to essentiality. The feature-values of each gene were correlated with the essentiality of the gene (1 = essential, 0 = non-essential). (A) shows the correlation coefficients for the topology features, (B) for the genomic and transcriptomic features. High values indicate that the feature was positively correlated to essentiality (see Additional file 2: SupplementS2 for all correlation coefficients). These values were obtained for all gold standards (ecoB, ecoG for E. coli and paeJ, paeL for P. aeruginosa).