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Figure 7 | BMC Systems Biology

Figure 7

From: An integrative multi-dimensional genetic and epigenetic strategy to identify aberrant genes and pathways in cancer

Figure 7

Deregulation of PTEN occurs differently between samples. In HCC1008 (top), PTEN is overexpressed with an associated gain in copy number and hypomethylation. Conversely, in HCC1395 (bottom), PTEN is underexpressed, with an associated loss in copy number, LOH, and DNA hypermethylation. This illustrates how each tumor may behave differently from another.

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