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Table 1 Model invalidation results for the Michaelis-Menten mechanism

From: Set-base dynamical parameter estimation and model invalidation for biochemical reaction networks

Initial Conditions Maximum Error
substrate ( s0) complex ( c0) σ [%]
0.999 0.001 ±14.0%
0.990 0.010 ±13.0%
0.900 0.100 ±8.5%
0.800 0.100 ±8.0%
0.800 0.200 ±5.0%
0.700 0.300 ±2.5%
0.600 0.400 ±0.5%
  1. Results of the model invalidation of the Michaelis-Menten mechanism. For each choice of initial conditions (concentration of substrate and complex), we report the largest error σ (in percentage) for which the resulting uncertain measurements allow to invalidate the Michaelis-Menten model.