Adjacent duplication subgraphs are correlated. Neighbouring relationships between links in the ancestral network can be of three kinds: (i) two links emerge from the same node (adjacent outgoing), (ii) two links point to the same node (adjacent incoming), (iii) two links are arranged head to tail (consecutive). The tables contain correlation significance scores measured with the WGD one-shot model for the co-occurrence of neighbour DSs of type ζ, β, and γ in the ancestral network. The significantly co-occurring pairs indicate that adjacent outgoing links tend to generate equal DSs (see Additional File 1, Fig. S2.) Adjacent incoming links preferentially produce two γ DSs, and consecutive links are significantly enriched in β DSs upstream of γ subgraphs; both configurations maintain full crosstalk between ancestral and newly formed pathways. See the duplication subgraph legend in Fig. 2.