Tissue co-expression of specific and shared genes with A) All interactors and B) Disease gene interactors. The Tissue Co-expression Index (TCI) was calculated for a disease gene and its interactor as the fraction of the 79 tissues analyzed in which both were detected as expressed. Larger indices indicate that disease gene and the interactor are co-expressed in most tissues. The fractions of disease genes shown as the function of TCI indicate that specific genes are more co-expressed with their interactors as well as disease gene interactors compared to shared genes. The error bars represent SEM.