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Table 3 Comparison of tissue co-expression of interactors of Essential genes with that of specific, shared, phenosim and phenodiv genes

From: Network properties of human disease genes with pleiotropic effects

Gene Class

Tissue co-expression of interactors

 

Mean ± S.D.

P-value *

Essential

46.4 ± 23.2

 

Specific

45.9 ± 24.6

0.42

Shared

42.4 ± 24.1

<0.001

Phenosim

42.5 ± 24.0

<0.001

Phenodiv

42.0 ± 22.9

<0.001

  1. *P-values were determined using Mann-Whitney U test