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Figure 4 | BMC Systems Biology

Figure 4

From: Robustness from flexibility in the fungal circadian clock

Figure 4

The model reproduces the systematic entrainment observed in LD cycles. A. Simulated variation of conidiation onset with photoperiod length. As in [16], conidiation onset was identified with the time ϕ FRQ at which FRQ has decreased to the approximate midpoint of its peak and trough values. Peak and trough times of frq mRNA and FRQ protein are also shown. White and grey regions denote light and dark respectively while the dotted line indicates the middle of the night. B. Dusk sensitivities ∂ϕ/∂t DUSK of the phase measures plotted in A for short and long days (see Additional file 1, Figure S2A for the sensitivities at intermediate photoperiods). The peak and trough times of frq mRNA are locked to either dusk (∂ϕ/∂t DUSK = 1) or dawn (∂ϕ/∂t DUSK = 0). By contrast, conidiation onset ϕ FRQ varies systematically with photoperiod (∂ϕ FRQ /∂t DUSK ≈ 0.5).

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