Figure 7
From: Identifying potential survival strategies of HIV-1 through virus-host protein interaction networks
Significantly over-represented network motifs in HIV-host protein interaction network. Black nodes are HIV proteins and white nodes are human proteins. Interactions can either be activations/up-regulations (+), inhibitions/down-regulations (-), activation/inhibition/regulation (±), or both (arrow without sign). N real is the number of specific motifs found. N rand ± SD is the average number and standard deviation of the motif found in one thousand randomized networks. P value is the probability that N real or more motifs are found in the randomized networks. Z score is the number of standard deviations N rand differs from N real . Network motifs were classified as significant when P value < 0.02 and Z score > 2.