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Table 5 Top one percent of proteins that have the highest score from the betweenness centrality metric.

From: Identifying potential survival strategies of HIV-1 through virus-host protein interaction networks

Name Definition Betweenness Score
TP53 [GenBank:NP_000537.3] tumor protein p53 44050
UBC [GenBank:NP_066289.2] ubiquitin C 36458
GRB2 [GenBank:NP_002077.1] growth factor receptor-bound protein 2 isoform 1 22792
BRCA1 [GenBank:NP_009225.1] breast cancer 1, early onset isoform 1 21622
SRC [GenBank:NP_005408.1] proto-oncogene tyrosine-protein kinase 21568
EGFR [GenBank:NP_005219.2 ] epidermal growth factor receptor isoform a 20472
STAT3 [GenBank:NP_644805.1] signal transducer and activator of transcription 3 isoform 1 18503
ESR1 [GenBank:NP_000116.2] estrogen receptor 1 18424
RB1 [GenBank:NP_000312.2] retinoblastoma 1 16777
PIK3R1 [GenBank:NP_852664.1] phosphoinositide-3-kinase, regulatory subunit, polypeptide 1 isoform 1 16048
POLR2A [GenBank:NP_000928.1] DNA directed RNA polymerase II polypeptide A 15896
MYC [GenBank:NP_002458.2] myc proto-oncogene protein 15608
SP1 [GenBank:NP_612482.2] Sp1 transcription factor 14620
RELA [GenBank:NP_068810.2] v-rel reticuloendotheliosis viral oncogene homolog A 14114
SHC1 [GenBank:NP_003020.2] Src homology 2 domain containing transforming protein 1 isoform p52Shc 14011