Table 1 Effect of evolutionary information on DNA-binding site prediction.
From: BindN+ for accurate prediction of DNA and RNA-binding residues from protein sequence features
Evolutionary Information | Accuracy(%) | Sensitivity(%) | Specificity(%) | Strength(%) | MCC | ROC AUC |
|---|---|---|---|---|---|---|
None | 70.4 | 69.5 | 70.6 | 70.0 | 0.295 | 0.761 |
| 72.0 | 71.3 | 72.1 | 71.7 | 0.323 | 0.779 |
| 74.8 | 73.4 | 75.0 | 74.2 | 0.365 | 0.813 |
| 71.1 | 70.0 | 71.3 | 70.7 | 0.306 | 0.771 |
| 76.2 | 72.4 | 76.8 | 74.6 | 0.377 | 0.817 |
PSSM | 77.7 | 74.8 | 78.2 | 76.5 | 0.409 | 0.849 |
PSSM + | 79.0 | 77.3 | 79.3 | 78.3 | 0.440 | 0.859 |
