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Table 1 Effect of evolutionary information on DNA-binding site prediction.

From: BindN+ for accurate prediction of DNA and RNA-binding residues from protein sequence features

Evolutionary Information Accuracy(%) Sensitivity(%) Specificity(%) Strength(%) MCC ROC AUC
None 70.4 69.5 70.6 70.0 0.295 0.761
72.0 71.3 72.1 71.7 0.323 0.779
74.8 73.4 75.0 74.2 0.365 0.813
71.1 70.0 71.3 70.7 0.306 0.771
76.2 72.4 76.8 74.6 0.377 0.817
PSSM 77.7 74.8 78.2 76.5 0.409 0.849
PSSM + 79.0 77.3 79.3 78.3 0.440 0.859