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Table 2 Effect of evolutionary information on RNA-binding site prediction.

From: BindN+ for accurate prediction of DNA and RNA-binding residues from protein sequence features

Evolutionary Information Accuracy(%) Sensitivity(%) Specificity(%) Strength(%) MCC ROC AUC
None 69.3 66.0 69.9 68.0 0.265 0.741
70.1 67.4 70.5 69.0 0.281 0.757
73.4 66.5 74.6 70.5 0.312 0.774
69.2 66.6 69.6 68.1 0.267 0.744
74.6 67.4 75.8 71.6 0.331 0.784
PSSM 76.8 71.5 77.7 74.6 0.380 0.818
PSSM + 77.7 71.6 78.7 75.2 0.393 0.825