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Table 2 Effect of evolutionary information on RNA-binding site prediction.

From: BindN+ for accurate prediction of DNA and RNA-binding residues from protein sequence features

Evolutionary Information

Accuracy(%)

Sensitivity(%)

Specificity(%)

Strength(%)

MCC

ROC AUC

None

69.3

66.0

69.9

68.0

0.265

0.741

70.1

67.4

70.5

69.0

0.281

0.757

73.4

66.5

74.6

70.5

0.312

0.774

69.2

66.6

69.6

68.1

0.267

0.744

74.6

67.4

75.8

71.6

0.331

0.784

PSSM

76.8

71.5

77.7

74.6

0.380

0.818

PSSM +

77.7

71.6

78.7

75.2

0.393

0.825