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Figure 2 | BMC Systems Biology

Figure 2

From: A conceptual cellular interaction model of left ventricular remodelling post-MI: dynamic network with exit-entry competition strategy

Figure 2

Effects of interaction strengths on the stability of the dynamic network with different interaction matrix ( P A → 1) Figure 2 demonstrates the evolutionary dynamics of a network with interaction matrix [1 0; 0 1], k=4, and initial populations of type A and type C cells are set as 9900 and 100 in a total population of 10000 cells, based on previously published experimental results. The intensity of selection ω equals to 0.01. In the left part of Figure 2 (Left), X axis represents the variable P A , the ratio of type A cellular population over the total population. The Y axis represents the evolutionary rate of type A cellular population denoted as A . The red star is the initial status of P A . At the initial status, A is positive, making P A increase until P A reaches 1 where A decreases to 0. In the right part of Figure 2 (Right), the simulation results demonstrate that population of type A cells increases until it dominates the whole population within 300 generations.

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