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Table 3 Simulation Results with No Missing Data

From: Non-compartment model to compartment model pharmacokinetics transformation meta-analysis – a multivariate nonlinear mixed model

   Estimate   
   TRUE(log-scale) Mean SE RelativeBias (%) 95% CP  
  V 1 3.5 3.505 0.110 0.14 0.89  
  k a 0.68 0.680 0.115 0.02 0.87  
Fixed-Effect k e -0.403 -0.397 0.112 0.75 0.89  
  k 12 -1.1 -1.097 0.088 0.24 0.93  
  k 21 -1.32 -1.322 0.053 0.15 0.99  
  V 1 0.09 0.083 0.045 8.05 0.97  
Between Study Variance k a 0.09 0.078 0.053 12.8 0.93  
  k e 0.09 0.085 0.045 5.33 0.96  
Sigma 2   0.01 0.01 0.003 4.43 0.95