Table 2 Predicted E2F-target genes from ~12K-size network that overlaps with previous studies by Ramirz-Parra et al. [30] and Vandepoele et al. [31].

1

At1g08130

ATLIG1

DNA recombination / DNA repair / DNA replication

-

√

2

At1g07370

PCNA1

Regulation of DNA replication and cell cycle

-

√

3

At1g67630

POLA2

DNA synthesis and replication

√

√

4

At2g07690

-

DNA synthesis and replication

√

-

5

At5g66750

CHR1

Transcriptional control/chromatin modification

√

-

6

At1g78650

POLD3

DNA or RNA metabolism/ transferase activity

√

√

7

At4g14700

ORC1A

Cell cycle, Replication control, DNA synthesis

√

-

8

At1g09450

-

N-terminal protein myristoylation/ protein amino acidPhosphorylation

√

-

9

At2g40550

ETG1

DNA replication

√

√

10

At1g67320

-

DNA replication, synthesis of RNA primer

-

√

11

At1g44900

-

DNA synthesis and replication, cell cycle control

√

√

12

At1g69770

CMT3

Chromatin silencing / DNA methylation

-

√

13

At2g21790

RNR1

DNA synthesis and replication

√

√

14

At2g16440

-

DNA replication initiation

-

√

15

At5g38110

ASF1B

Transcriptional control

√

√

16

At5g52950

ATIM

Putative protein

√

-

17

At5g18620

CHR17

Transcriptional control, chromatin modification

√

√

18

At5g52910

ATIM

Regulation of circadian rhythm

√

√

19

At2g24490

RPA2

Replication protein A-like

-

√

20

At2g29570

PCNA2

Error-prone postreplication DNA repair / replication

-

√

21

At2g31270

CDT1A

Chloroplast organization / DNA replication

-

√

22

At3g02820

-

Response to DNA damage stimulus / cell cycle

-

√

23

At3g18630

-

DNA repair

-

√

24

At3g25100

CDC45

Cell division control protein

-

√

25

At5g49010

SLD5

DNA replication initiation / GINS complex

-

√

26

At5g49160

MET1

DNA or RNA metabolism / other cellular processes

-

√

27

At5g62410

SMC2

Cell organization / DNA or RNA metabolism

-

√

28

At5g63960

-

DNA or RNA metabolism / nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

-

√

29

At5g67100

ICU2

Negative regulation of flower development / leaf morphogenesis

-

√

30

At1g35530

-

helicase activity/ hydrolase activity / DNA binding

-

√

31

At3g02920

-

nucleic acid binding

-

√

32

At3g27640

-

nucleotide binding

-

√

33

At5g06590

-

Unknown

-

√

34

At5g63920

-

DNA metabolic process / DNA unwinding duringReplication

-

√