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Figure 4 | BMC Systems Biology

Figure 4

From: Genome-scale reconstruction and in silico analysis of the Ralstonia eutropha H16 for polyhydroxyalkanoate synthesis, lithoautotrophic growth, and 2-methyl citric acid production

Figure 4

Flux solution space of wild-type and mutants ( ΔprpB, ΔprpD , or ΔacnM ) of R. eutropha. Based on the flux solution space of wild-type, 2-methylcitric acid is non-growth associated metabolite when the cell growth rate is maximized. After the in silico single knockout of each gene, 2-methylcitric acid is changed to the growth-associated metabolite according to the flux solution space of the mutants. The x and y axes indicate the relative flux (%) of 2-methylcitric acid production rate and cell growth rate that are normalized to the maximum values of 2-methylcitric acid production rate and cell growth rate in the wild-type of R. eutropha, respectively.

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BMC Systems Biology

ISSN: 1752-0509

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