Figure 2
From: Combined logical and data-driven models for linking signalling pathways to cellular response
Experimental dataset in (a) Huh7 hepatocellular carcinoma cell type and (b) primary hepatocytes. Top panels correspond to the signalling dataset. Each small subplot consists of two datapoints: the zero "unstimulated" condition and the "early response" which is the average phosphorylation activity at 5 and 25 minutes post-stimuli treatment. Bottom panels correspond to the response dataset where 22 cytokines were measured 24 hours post-stimuli. The red colour intensity is proportional to the percent increase of the cytokine release as compared to the basal (unstimulated) condition.