Figure 3
The metabolite connectivity of iAB-RBC-283, Recon 1, and the similarly sized organelles in Recon 1. Recon 1 and the mitochondria have high network connectivity, with many data points above the reference lines. The erythrocyte network and other organelles have less metabolic connectivity denoted by data point being on or below the reference lines. This characteristic can be attributed to either 1) an inherently 'fragmented' erythrocyte network, or 2) incomplete proteomic coverage.