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Figure 1 | BMC Systems Biology

Figure 1

From: An Integrated Mathematical Model of Thrombin-, Histamine-and VEGF-Mediated Signalling in Endothelial Permeability

Figure 1

Framework of integrated pathway simulation model of thrombin-, histamine-, and VEGF-mediated MLC activation. The components in existing models are highlighted by red, blue, and red + blue + green background colour for models from reference 15, 16 and 18 respectively. The protein in the gray box represents output signalling. ROCK (f) and ROCK (o) refer to ROCK in folded and open conformation respectively.

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