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Table 1 Comparison of the areas with respect to different time ranges in Figure 8

From: An Integrated Mathematical Model of Thrombin-, Histamine-and VEGF-Mediated Signalling in Endothelial Permeability

MLC activation curve Area under MLC activation curve with respect to different time range (time unit:min)
  0-10 10-20 20-30 30-40 40-50 50-60 60-70 70-80
Curve 1:Histamine + Thrombin induced activation 5.9 7.8 7.6 6.9 6.1 5.2 4.7 4.0
Curve 2:Histamine-mediated activation 4.3 3.1 2.6 2.3 2.0 1.6 1.4 1.3
Curve 3:Thrombin-mediated activation 4.4 3.4 3.2 3.1 3.1 3.0 3.0 2.9
Simple sum of curve 2 and 3 8.7 6.5 5.8 5.4 5.0 4.7 4.5 4.3
Area difference between curve 1 and simple sum of curve 2 and 3 -2.8 1.3 1.8 1.5 1.1 0.6 0.2 -0.3
  1. Comparison of the areas under the thrombin and histamine induced MLC activation curve with those of thrombin-induced and histamine-induced MLC activation curves with respect to different time ranges in Figure 8.