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Figure 6 | BMC Systems Biology

Figure 6

From: Global transcription regulation of RK2 plasmids: a case study in the combined use of dynamical mathematical models and statistical inference for integration of experimental data and hypothesis exploration

Figure 6

Concentration Control Coefficients. Concentration control coefficients for a) KorA and b) KorB shows the sensitivity of the model to each parameter: kA - KorA synthesis rate, kB - KorB synthesis rate, k1-affinity of OA1, k2 - affinity of OB1, k3 - affinity of KorA to KorB-DNA complex, k4 - affinity of KorB to KorA-DNA complex, σ A , σ B - monomerization rates for KorA and KorB, respectively, λA, λB - dimerization rate for KorA and KorB, respectively, γP - protein turnover. The synthesis and turn-over rates are particularly important while the dimerization and monomerization rates are unimportant.

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BMC Systems Biology

ISSN: 1752-0509

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