Figure 7

Dependence of the unrepressed to repressed ratio on the copy number of plasmids. Models: brown - 0u, red - u0, blue - uu, purple - 11. The reported 91.8-fold repression ratio is shown as a horizontal line. The ratios for the u0 and uu models cross this line at a realistic plasmid copy number. The 0u model crosses the line at an unrealistically low plasmid copy number, and the 00 model has much higher ratios (data not shown). The 11 model crosses the line at an unrealistically high plasmid copy number; models: the first and second signs stand for expression from complexes when KorA or KorB are bound to the DNA, respectively, 1 - no repression, u - partial repression, 0 - total repression.