Figure 1
Work flow. We compared a sensitivity analysis of the original model (Track 1) to predictions from the hybrid model (Track 2) using the same set of 470 perturbations of original model parameters. Track 1: For each perturbation i) a numerical simulation was performed; ii) output measures were retrieved (cycle time t
CT
and cell mass M
end
) and; iii) sensitivity scores (
and 
) were constructed for each parameter. Track 2: For each perturbation of the original model i) a corresponding recalibration of the hybrid model parameters was performed; ii) the analytical constraints (NC and SF) were recalculated and; iii) sensitivity scores (
and 
) were constructed for each original parameter.