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Figure 3 | BMC Systems Biology

Figure 3

From: When the human viral infectome and diseasome networks collide: towards a systems biology platform for the aetiology of human diseases

Figure 3

Cellular connectivity (k h ) and centrality (b h ) of Essential Host Factors (EHFs). The histograms show the average cellular connectivity (left - kh) and centrality (right - bh) of Essential Host Factors (EHFs) computed for the group of proteins directly interacting with viruses (left; red bars - TP) and for the groups of proteins indirectly targeted by viruses, (right; orange bars - TP-N). Values are compared to average values of connectivity and centrality computed for a control dataset of not-Essential Host Factors (NOT-EHFs). Distribution differences are statistically assessed using one-tailed Wilcoxon test (P-Values < 0.05 *).

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