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Table 2 Percentage of reinitiation at GCN4 as observed in experiments and predicted by Model 1

From: Analysing GCN4 translational control in yeast by stochastic chemical kinetics modelling and simulation

 

Mutant 1

Mutant 2

Mutant 3

Mutant 4

 

n 1

n 2

n 1

n 2

n 1

n 2

n 1

n 2

GCN4-lacZ Mutants

32

151

32

294

200

100

200

150

DR(%) measureda (predicted)

38.8 (48.4)

55.4 (68.3)

13.7 (13.9)

27.9 (18.5)

R(%) measureda (predicted)

14.1 (17.6)

30.3 (21.8)

1.23 (0.0115)

2.81 (0.0121)

  1. aConstruct is depicted in Figure 1C (contains uORF4 and GCN4). Calculated using published data from [5] by Equation 2.