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Table 2 Conservation rates of edges in different types of networks between S.cerevisiae and S. pombe

From: Biological interaction networks are conserved at the module level

   From S. cerevisiae to S. pombe From S. pombe to S. cerevisiae
   Baseline BMI WMI Extended WMI Baseline BMI WMI Extended WMI
Integrated Real 18.11 16.17 46.54 49.66 22.18 20.16 29.94 31.97
  Rand 9.13 ± 0.04 9.26 ± 0.32 4.66 ± 0.48 5.22 ± 0.49 11.99 ± 0.06 13.31 ± 0.30 7.38 ± 0.57 7.71 ± 0.59
Integrated
(no-seqs)
Real 16.89 15.61 38.54 40.99 20.86 15.88 34.25 35.03
  Rand 9.04 ± 0.05 9.68 ± 0.30 4.57 ± 0.50 5.05 ± 0.52 11.84 ± 0.05 12.72 ± 0.21 8.01 ± 0.60 8.34 ± 0.61
Integrated(exclude-para) Real 16.84 15.59 38.44 40.89 20.77 15.83 34.06 34.84
  Rand 8.92 ± 0.05 9.58 ± 0.30 4.47 ± 0.49 5.38 ± 0.53 11.79 ± 0.05 12.68 ± 0.21 7.95 ± 0.60 8.24 ± 0.60
Coexpression Real 19.27 18.27 36.28 40.26 19.51 18.76 20.30 21.74
  Rand 10.32 ± 0.05 10.2 ± 0.38 6.71 ± 0.78 7.12 ± 0.75 11.09 ± 0.05 12.27 ± 0.30 8.06 ± 0.70 8.46 ± 0.71
PPI Real 1.78 1.46 5.82 25.90 57.96 56.94 71.02 76.33
  Rand 0.06 ± 0.01 0.06 ± 0.02 0.05 ± 0.09 1.42 ± 0.43 3.12 ± 0.42 3.70 ± 1.10 2.31 ± 1.33 2.62 ± 1.48
Positive GI Real 2.24 1.77 8.28 33.93 10.02 8.26 21.20 36.96
  Rand 0.30 ± 0.05 0.29 ± 0.09 0.15 ± 0.19 1.68 ± 0.61 1.43 ± 0.27 1.50 ± 0.45 1.19 ± 1.27 1.73 ± 1.50
Negative GI Real 2.86 2.60 7.53 43.08 15.14 14.67 32.90 56.77
  Rand 1.09 ± 0.05 0.96 ± 0.13 1.37 ± 1.96 2.89 ± 2.78 7.56 ± 0.29 7.17 ± 0.71 9.95 ± 10.16 10.98 ± 10.68
GO Real 26.59 26.41 45.87 61.69 31.81 31.47 39.70 57.81
  Rand 2.23 ± 0.08 2.16 ± 0.13 2.27 ± 2.12 3.78 ± 2.96 4.05 ± 0.11 4.28 ± 0.15 4.11 ± 2.58 5.22 ± 2.88
Sequence Real 90.16 90.18 90.15 97.33 76.92 51.40 79.73 89.66
  Rand 17.55 ± 0.64 25.61 ± 1.6 1.23 ± 0.76 1.96 ± 0.86 14.53 ± 0.39 28.88 ± 1.59 0.09 ± 0.15 0.34 ± 0.30
  1. Conservation rates are listed for the following categories: Baseline: the entire networks; BMI: Between-Module Interactions; WMI: Within-Module Interactions; Extended WMI: extended module interactions. (no-seqs): statistics based on integrated network that does not include the sequence network. (exclude-para): in addition to 'no-seqs', all edges connecting paralogs (nodes with BLASTP E-value cutoff of 1e-25 or less) were removed.