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Table 5 Comparison of top 10 late down regulated genes

From: Meta-analysis of estrogen response in MCF-7 distinguishes early target genes involved in signaling and cell proliferation from later target genes involved in cell cycle and DNA repair

Gene

M

gse3529

gse3834

gse4006

gse4025

gse6800

gse8597

gse9936

IL17RB

1

*

*

8

5

*

12

2

TFF1

2

*

*

92

19

*

655

1

CDK1

3

*

59

28

13

*

57

5

MYBL1

4

1

6

31

174

*

1

162

CDC20

5

43

3

*

15

*

310

3

CXCL12

7

15

8

135

68

*

17

57

PBK

8

39

16

*

18

*

23

33

RAB31

9

29

*

14

4

*

93

25

KIF2C

10

*

63

*

7

*

226

4

PDZK1

419

2

25

57

*

*

414

*

GREB1

19

3

1

1

194

1

62

323

EGR3

184

4

42

41

*

4

19

*

AREG

*

5

7

38

*

21

46

719

NPY1R

57

6

*

13

*

*

187

96

MSMB

1650

7

*

*

*

*

*

*

RASGRP1

*

8

*

*

*

*

1020

*

FABP5

*

9

*

*

*

23

98

*

CELSR2

136

10

33

89

*

26

313

402

DHRS2

294

*

2

21

*

*

639

542

PTTG1

29

*

4

*

77

*

346

14

KIF20A

18

*

5

*

17

*

304

7

PLK1

74

*

9

*

45

*

389

44

CENPA

15

71

10

*

39

*

270

9

GJA1

*

*

*

2

*

*

*

*

WISP2

549

*

67

3

*

*

342

*

ASCL1

704

*

*

4

*

*

*

400

OLFML3

65

*

*

5

114

*

*

29

EPB41L3

605

*

*

6

*

*

*

357

PEG10

567

*

*

7

*

*

*

505

PGR

628

*

*

10

*

*

94

*

PRIM1

12

*

*

*

1

*

56

15

SLC7A5

107

*

*

*

2

24

*

132

PLAC1

17

*

*

132

3

*

13

53

TPD52L1

14

32

*

97

6

19

363

39

KIF4A

21

*

*

*

8

*

148

8

TPX2

36

*

40

*

10

*

244

34

SLC26A2

293

*

66

109

*

2

290

*

PRSS23

101

21

*

61

61

3

675

246

PTP4A1

709

*

*

*

*

5

*

966

CA12

30

55

*

65

44

6

249

60

HSPB8

1739

40

32

*

*

7

*

*

TSKU

*

*

*

*

*

9

*

*

SGK3

93

22

*

23

*

*

2

778

UGT2B15

112

*

*

26

*

*

3

227

TMPRSS3

220

16

*

56

*

22

4

*

PCP4

255

*

*

*

*

*

5

867

MCM10

92

41

*

*

200

*

6

243

DSCC1

132

62

*

*

*

*

7

453

EXO1

338

*

*

*

*

*

8

*

DTL

53

*

*

79

261

*

9

95

CENPI

463

*

*

*

*

*

10

*

DLGAP5

25

*

17

*

54

*

159

10

  1. The column gene includes a union of top 10 regulated genes from individual studies and meta-analysis. The ranks of these genes are indicated in the individual study and in the meta analysis studies. The asterisk * indicates that the gene was not included in the significant list (pfp ≤ 0.05).